Diesel exhaust particles disturb gene expression in mouse testis
نویسندگان
چکیده
منابع مشابه
Experimental Study on Diesel Exhaust Particles Agglomeration Using Acoustic Waves
Diesel exhaust particles are a complex mixture of thousands of gases and fine substances that contain more than 40 different environmental contaminants. Being exposed to these exhaust particles (called soot) can cause lung damage and respiratory problems. Diesel particulate filters are used in many countries for mobile sources as a legal obligation to decrease harmful effect of these fine pa...
متن کاملDiesel exhaust particles block induction of oral tolerance in mice.
We investigated the effect of diesel exhaust particles (DEP) on oral tolerance. Oral tolerance was induced by feeding mice with 10 mg of hen egg lysozyme (HEL) daily over a period of 5 days before immunization with the antigen. Varying doses of DEP were orally administered immediately before each feeding of HEL. The results showed that oral administration of HEL significantly suppressed product...
متن کاملDiesel exhaust particles in the work environment and their analysis.
Diesel engines are widely used in industries, for example transportation, mining, and construction, because they efficiently produce high power. In diesel exhaust particles (DEP), the number of ultrafine particles, less than around 100 nm, is dominant in contrast to mass size distribution. Carcinogenic PAHs may be adsorbed on DEP at high concentrations. As occupational exposure usually occurs n...
متن کاملLong-Term Effects of Diesel Exhaust Particles on Airway Inflammation and Remodeling in a Mouse Model
PURPOSE Diesel exhaust particles (DEPs) can induce and trigger airway hyperresponsiveness (AHR) and inflammation. The aim of this study was to investigate the effect of long-term DEP exposure on AHR, inflammation, lung fibrosis, and goblet cell hyperplasia in a mouse model. METHODS BALB/c mice were exposed to DEPs 1 hour a day for 5 days a week for 3 months in a closed-system chamber attached...
متن کاملDiesel exhaust particles in lung acutely enhance experimental peripheral thrombosis.
BACKGROUND Pollution by particulates has consistently been associated with increased cardiovascular morbidity and mortality, but a plausible biological basis for this association is lacking. METHODS AND RESULTS Diesel exhaust particles (DEPs) were instilled into the trachea of hamsters, and blood platelet activation, experimental thrombosis, and lung inflammation were studied. Doses of 5 to 5...
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ژورنال
عنوان ژورنال: Environmental Toxicology
سال: 2007
ISSN: 1520-4081,1522-7278
DOI: 10.1002/tox.20234